Depression is now classified as the leading cause of disability worldwide, with an estimated 3 people in every 100 in Asia having depression. The coronavirus is presenting new and unique challenges to this emerging disability. We are navigating unchartered waters with this pandemic, and the Philippines is no exception. It is crucial to find new ways to work and interact while caring for our mental health and well-being. This research aims to discuss the mental health and well-being of employees at the time of the pandemic. Specifically, this study seeks to understand the factors and signs contributing to employee depression while working from home. How can Human Resource Department extend its assistance by checking the digital wellness of employees? Two hundred two (202) work from home employees joined the survey from Greater Manila Area. Using the enhanced Depression Model, HR support positively affects self-esteem but negatively affects work from home stress. Indeed, work-from-home-related stress positively affects depression signs. It is essential to understand the well-being of our employees in the time of COVID-19 due to the blurring lines of work-life balance, including its context, to be able to empathize and reach out to the organization’s workforce.
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